Establishment of an IL-2-dependent, antigen nonspecific chicken T-cell line
✍ Scribed by Catherine Corbel; Jean-Léon Thomas
- Book ID
- 119077070
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- English
- Weight
- 496 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0145-305X
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
A continuous cell line was established from the blood of a patient (HH) with an aggressive cutaneous T-cell leukemia/ lymphoma who lacked antibodies to human T lymphotrophic virus, type 1. The immunophenotype of the cultured cells was CD2+, CD3+, CD4+, CD5+, CD8-, DR' and CD25-(Tac, IL-2 receptor a
The establishment of IL-2-independent T-cell lines spontaneously derived from long-term IL-2-dependent cytotoxic T-cell lines is described. Two lines (cloned and uncloned) studied in detail have shown the following characteristics: (1) Permanent loss of IL-2 dependence. (2) Partial or complete loss