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Erythrocyte catechol-O-methyltransferase activity in a Swedish population

✍ Scribed by Ylva Floderus; Svante B. Ross; Lennart Wetterberg

Book ID
119839167
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
279 KB
Volume
19
Category
Article
ISSN
0009-9163

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Catechol-O-methyltransferase (COMT) catalyzes the O-methylation of catechol hormones, neurotransmitters and certain drugs. It is subject to genetic polymorphism and ethnic differences. High red blood cell (RBC) COMT activity has been correlated with a poor response to levodopa treatment in Parkinson