Degradative activities in a recombinant
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Mio-Sam Lao; Derek Toth; Glenys Danell; Calvin Schalla
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Article
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1996
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Springer
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English
โ 700 KB
Two degradative activities were found in a recombinant Chinese hamster ovary cell culture. These activities became more dominant under high cell density and extended running time, as achieved in a semi-continuous perfusion culture. The first, insulin degradative activity caused a growth upset in the