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Recombinant porcine prorelaxin produced in Chinese hamster ovary cells is biologically active

โœ Scribed by Ann L. Vu; Carla B. Green; Katherine F. Roby; Michael J. Soares; David T.W. Fei; Anthony B. Chen; Simon C.M. Kwok


Book ID
118345980
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
496 KB
Volume
52
Category
Article
ISSN
0024-3205

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Two degradative activities were found in a recombinant Chinese hamster ovary cell culture. These activities became more dominant under high cell density and extended running time, as achieved in a semi-continuous perfusion culture. The first, insulin degradative activity caused a growth upset in the