𝔖 Bobbio Scriptorium
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Ergosterol biosynthesis inSaccharomyces cerevisiae

✍ Scribed by Karst, Francis ;Lacroute, François

Book ID
104813786
Publisher
Springer
Year
1977
Tongue
English
Weight
811 KB
Volume
154
Category
Article
ISSN
0026-8925

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6-Azauracil inhibition of GTP biosynthes
6-Azauracil inhibition of GTP biosynthesis inSaccharomyces cerevisiae
✍ Françoise Exinger; François Lacroute 📂 Article 📅 1992 🏛 Springer-Verlag 🌐 English ⚖ 437 KB

The addition of 6-azauracil to the growth medium causes a strong reduction of the GTP level in the nucleotide pool of Saccharomyces cerevisiae. In-vitro experiments show a strong inhibition of IMP dehydrogenase activity by 6-azaUMP explaining the preceeding effect. PPR2 mutants, previously character