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ERCC1 and its role in tumor pathogenesis and progression

✍ Scribed by Kapoor, Shailendra


Book ID
120042719
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
139 KB
Volume
31
Category
Article
ISSN
1078-1439

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Thrombospondin (TSP-1) is a large glycoprotein secreted by platelets and synthesized by many cell types, including endothelial and tumor cells. Although controversy exists about the biological function of TSP-1, the following observations suggest that TSP-1 may potentiate tumor progression. (1) Tumo