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Equilibrium Thermodynamics of Cell-Cell Adhesion Mediated by Multiple Ligand-Receptor Pairs

✍ Scribed by Coombs, Daniel; Dembo, Micah; Wofsy, Carla; Goldstein, Byron

Book ID
118516008
Publisher
Biophysical Society
Year
2004
Tongue
English
Weight
233 KB
Volume
86
Category
Article
ISSN
0006-3495

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## Abstract A continuum model was proposed to simulate a biological cell adhering to a substrate surface domain with selectively coated ligands. Cell adhesion was modeled by a traction‐separation law depending on the receptor‐ligand distance and their densities. It was found that the obtained sprea