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Equilibria of the 5-Substituted-1,2-acylated Tetrazoles and Imidoyl Azides †

✍ Scribed by Dabbagh, Hossein A.; Lwowski, Walter


Book ID
118059397
Publisher
American Chemical Society
Year
2000
Tongue
English
Weight
95 KB
Volume
65
Category
Article
ISSN
0022-3263

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Copper-catalyzed synthesis of 5-substitu
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The [3+2] cycloaddition between various nitriles and trimethylsilyl azide proceeds smoothly in the presence of a Cu I catalyst in DMF/ MeOH, to give the corresponding 5-substituted 1H-tetrazoles in good to high yields. The reaction most probably proceeds through the in situ formation of a copper azi