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Synthesis of 5-Substituted 1H-Tetrazoles by the Copper-Catalyzed [3+2] Cycloaddition of Nitriles and Trimethylsilyl Azide

✍ Scribed by Tienan Jin; Fukuzou Kitahara; Shin Kamijo; Yoshinori Yamamoto


Book ID
112005510
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
302 KB
Volume
3
Category
Article
ISSN
1861-4728

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πŸ“œ SIMILAR VOLUMES


ChemInform Abstract: Synthesis of 5-Subs
✍ Tienan Jin; Fukuzou Kitahara; Shin Kamijo; Yoshinori Yamamoto πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons βš– 31 KB πŸ‘ 2 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a β€œFull Text” option. The original article is trackable v

Copper-catalyzed synthesis of 5-substitu
✍ Tienan Jin; Fukuzou Kitahara; Shin Kamijo; Yoshinori Yamamoto πŸ“‚ Article πŸ“… 2008 πŸ› Elsevier Science 🌐 French βš– 135 KB

The [3+2] cycloaddition between various nitriles and trimethylsilyl azide proceeds smoothly in the presence of a Cu I catalyst in DMF/ MeOH, to give the corresponding 5-substituted 1H-tetrazoles in good to high yields. The reaction most probably proceeds through the in situ formation of a copper azi

Regiospecific synthesis of 2-allylated-5
✍ Young Soo Gyoung; Jae-Goo Shim; Yoshinori Yamamoto πŸ“‚ Article πŸ“… 2000 πŸ› Elsevier Science 🌐 French βš– 137 KB

A variety of 2-allylated-5-substituted tetrazoles were prepared in excellent yields through the reaction of alkyland arylidenemalononitriles, allyl acetates and trimethylsilyl azide in the presence of a palladium catalyst.