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Epimerization of benzo[a]pyrene-tetrols after acid hydrolysis, implications for determination of benzo[a]pyrene adducts in protein and DNA

✍ Scribed by Gulshan Ara Islam; Tyge Greibrokk; Frode Rise; Steinar Øvrebø

Book ID
114072441
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
178 KB
Volume
423
Category
Article
ISSN
0027-5107

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Liquid chromatographic analysis and stability of benzo[a]pyrene-tetrols in blood protein adducts in rats after exposure to benzo[a]pyrene
✍ Eugène H.J.M. Jansen; Rijk H. van den Berg; E. Dinant Kroese 📂 Article 📅 1994 🏛 Elsevier Science 🌐 English ⚖ 534 KB

The stability of the four benzojalpyrene-7,8,9,10-tetrahydrotetrols is investigated under hydrolysis conditions necessary to release the tetrols from haemoglobin. Two benzo[alpyrene (BP)-tetrols appeared to be rather stable under hydrolysis conditions, whereas two other BP-tetrols were unstable and