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HPLC analysis of benzo[a]pyrene-albumin adducts in benzo[a]pyrene exposed rats. Detection of cis-tetrols arising from hydrolysis of adducts of anti- and syn-BPDE-III with proteins

✍ Scribed by Gulshan Ara Islam; Tyge Greibrokk; Ronald G Harvey; Steinar Øvrebø

Book ID
114009803
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
223 KB
Volume
123
Category
Article
ISSN
0009-2797

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✍ Eugène H.J.M. Jansen; Rijk H. van den Berg; E. Dinant Kroese 📂 Article 📅 1994 🏛 Elsevier Science 🌐 English ⚖ 534 KB

The stability of the four benzojalpyrene-7,8,9,10-tetrahydrotetrols is investigated under hydrolysis conditions necessary to release the tetrols from haemoglobin. Two benzo[alpyrene (BP)-tetrols appeared to be rather stable under hydrolysis conditions, whereas two other BP-tetrols were unstable and