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Epigenetic inactivation of connexin 32 in renal cell carcinoma from hemodialytic patients

✍ Scribed by Yano, Tomohiro; Ito, Fumio; Yamasaki, Hiroshi; Hagiwara, Kiyokazu; Ozasa, Hisashi; Nakazawa, Hayakazu; Toma, Hiroshi

Book ID
109066787
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
37 KB
Volume
65
Category
Article
ISSN
0085-2538

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## Abstract We have previously reported that connexin (Cx) 32 gene, a member of gap junctions, was specifically downregulated in human renal cell carcinoma (RCC) and it acts as a tumor suppressor against RCC. Because there is no standard therapy for advanced RCC, we investigated the anti‐metastatic