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Epigallocatechin gallate prevents autoimmune diabetes induced by multiple low doses of streptozotocin in mice

โœ Scribed by Eun -Kyung Song; Hyeon Hur; Myung -Kwan Han

Publisher
Springer
Year
2003
Tongue
English
Weight
574 KB
Volume
26
Category
Article
ISSN
0253-6269

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The imbalance of Th1/Th2 subsets is an important pathogenic mechanism for insulin-dependent diabetes mellitus (IDDM). Calcitonin gene-related peptide (CGRP) has been found to play important roles in the regulation of T lymphocytes. We hypothesize that exogenous CGRP administration during insulitis m