Induction of experimental autoimmune diabetes by low-dose streptozotocin treatment in genetically resistant mice
✍ Scribed by U. Kiesel; B. Greulich; C.Marx-Soho Moumé; H. Kolb
- Publisher
- Elsevier Science
- Year
- 1981
- Tongue
- English
- Weight
- 268 KB
- Volume
- 3
- Category
- Article
- ISSN
- 0165-2478
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
In mice, an experimental autoimmune diabetes can be induced by multiple injections with low doses of streptozotocin. Since different mouse strains show a varying susceptibility towards this treatment, we have examined whether the experimental autoimmune diabetes is under the genetic control of the m
The imbalance of Th1/Th2 subsets is an important pathogenic mechanism for insulin-dependent diabetes mellitus (IDDM). Calcitonin gene-related peptide (CGRP) has been found to play important roles in the regulation of T lymphocytes. We hypothesize that exogenous CGRP administration during insulitis m