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Epidermal Growth Factor Receptor-Related Protein Inhibits Cell Growth and Induces Apoptosis of BxPC3 Pancreatic Cancer Cells

✍ Scribed by Zhang, Y.


Book ID
126019140
Publisher
American Association for Cancer Research
Year
2005
Tongue
English
Weight
417 KB
Volume
65
Category
Article
ISSN
0008-5472

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Pancreatic cancer cells are usually resistant to apoptosis induced by cytotoxic drugs, by activation of surface receptors such as Fas and TNF receptor or by serum or growth factor withdrawal. Actinomycin D (actD) is an inhibitor of RNA synthesis and acts as a potent inducer of apoptosis in several c