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Inhibition of epidermal growth factor receptor kinase induces protease-dependent apoptosis in human colon cancer cells

✍ Scribed by William E. Karnes Jr.*; Shaun G. Weller*; Philip N. Adjei*; Timothy J. Kottke‡; Kahlil S. Glenn*; Gregory J. Gores*; Scott H. Kaufmann‡


Book ID
118520265
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
396 KB
Volume
114
Category
Article
ISSN
0016-5085

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Epidermal growth factor expression in hu
✍ Sriram Rajagopal; Shuang Huang; Thomas L. Moskal; Bang-Ning Lee; Adel K. El-Nagg 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 French ⚖ 961 KB

## Abstract Human colon cancer cell lines express epidermal growth factor (EGF) mRNA, secrete EGF and may respond to it __via__ the cell‐surface EGF receptor (EGFR). Expression of these molecules in human colon and colon tumor, however, is not clear. Reverse transcription‐polymerase chain reaction