𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Epidermal growth factor receptor lacking C-terminal autophosphorylation sites retains signal transduction and high sensitivity to epidermal growth factor receptor tyrosine kinase inhibitor

✍ Scribed by Mari Maegawa; Tokuzo Arao; Hideyuki Yokote; Kazuko Matsumoto; Kanae Kudo; Kaoru Tanaka; Hiroyasu Kaneda; Yoshihiko Fujita; Fumiaki Ito; Kazuto Nishio


Book ID
108586405
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
359 KB
Volume
100
Category
Article
ISSN
1347-9032

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Epidermal growth factor receptor mutatio
✍ Victor Cohen; Jason S. Agulnik; Celina Ang; Goulnar Kasymjanova; Gerald Batist; 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 206 KB 👁 1 views

## Abstract ## BACKGROUND: Somatic mutations in the epidermal growth factor receptor (EGFR) kinase domain are associated with sensitivity to EGFR‐tyrosine kinase inhibitors (EGFR‐TKI) in patients with nonsmall cell lung cancer (NSCLC). ## METHODS: The authors tested the possibility that nucleoti

Syntheses of [14C] and [2H4]PD0205520, a
✍ Yinsheng Zhang; Yun Huang; Che C. Huang 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 French ⚖ 142 KB

## Abstract 5‐(4‐Methyl‐piperazin‐1‐yl)‐pent‐2‐ynoic acid [4‐(3‐chloro‐4‐fluoro‐phenylamino)‐pyrido[3,4‐d]pyrimidin‐6‐yl]‐amide, PD0205520, was under investigation as a potential inhibitor of the tyrosine kinase (TK) activity of the epidermal growth factor receptor (EGFR) for cancer treatment. Both