Eosinophil as antigen-presenting cell: activation of T cell clones and T cell hybridoma by eosinophils after antigen processing
✍ Scribed by Victoria Del Pozo; Belen de Andrés; Elena Martín; Blanca Cárdaba; Julio Cesar Fernández; Soledad Gallardo; Paloma Tramón; Pilar Palomino; Carlos Lahoz; Francisco Leyva-Cobian
- Publisher
- John Wiley and Sons
- Year
- 1992
- Tongue
- English
- Weight
- 794 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0014-2980
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
T cell lines and T cell clones derived from inbred Fischer rats and specific for Schistosoma mansoni antigens were established. Cell-free supernatants from the T cell lines demonstrated a marked capacity to enhance IgE-and IgGa-dependent eosinophil-mediated killing of S. mansoni larvae in vitro. In
Most antigens recognized by T cells require unfolding or partial degradation (processing) followed by association with Major Histocompatibility Complex (MHC) molecules. We examined the processing requirements for the presentation of antigen to two T cell hybridomas which recognize the alpha-helical