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Enzyme-Catalyzed Hydrolysis of Bicycloheptane and Cyclobutene Diesters to Monoesters

✍ Scribed by Guo, Zhiwei; Wong, Michael Kwok Y.; Hickey, Matthew R.; Patel, Bharat P.; Qian, Xinhua; Goswami, Animesh


Book ID
125543922
Publisher
American Chemical Society
Year
2013
Tongue
English
Weight
223 KB
Volume
18
Category
Article
ISSN
1083-6160

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## Abstract (±)‐__anti__‐2,4‐Dimethylpentanedioic anhydride (__rac__‐1) was converted in good yields and with high enantiomeric excess by an enzyme‐catalyzed sequential esterification into the (2__R__,4__R__)‐monoester 2 and the (2__S__,4__S__)‐diester __ent__‐3. Best results were obtained with Nov