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Enzymatic Synthesis of Peptides with Hydrophilic Amino Acid in Water-Miscible Organic Solvent

✍ Scribed by YUKTTAKA KIMURA; YOSHIKO TARI; SHUJI ADACHI; RYUICHI MATSUNO


Book ID
119867711
Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
180 KB
Volume
672
Category
Article
ISSN
0890-6564

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V8 proteinase-catalyzed peptide synthesi
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Free Staphylococcus auseus V8 proteinase was applied to coupling reactions of Z-Glu-OMe, Z-Glu-OBzl, Z-Ala-Glu-OMe and Z-Ala-Ala-Glu-OMe with various amino acid amides and peptides in acetonitrile containing 5 vol. % of water. No synthesis of Z-Asp-Leu-NH, was achieved under the same conditions. The