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Enzymatic reactions in aqueous-organic media. VI. Peptide synthesis by α-chymotrypsin in hydrophilic organic solvents

✍ Scribed by Kisee, Hideo; Fujimoto, Keiichi; Noritomi, Hidetaka


Book ID
122750463
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
569 KB
Volume
8
Category
Article
ISSN
0168-1656

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Peptide synthesis catalyzed by polyethyl
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Chymotrypsin modified with polyethylene glycol was successfully used for peptide synthesis in organic solvents. The benzene-soluble modified enzyme readily catalyzed both aminolysis of N-benzoyl-L-tyrosine p-nitroanilide and synthesis of N-benzoyl-L-tyrosine butylamide in the presence of trace amoun