Chymotrypsin modified with polyethylene glycol was successfully used for peptide synthesis in organic solvents. The benzene-soluble modified enzyme readily catalyzed both aminolysis of N-benzoyl-L-tyrosine p-nitroanilide and synthesis of N-benzoyl-L-tyrosine butylamide in the presence of trace amoun
✦ LIBER ✦
Enzymatic peptide syntheses in organic solvent mediated by modified α-chymotrypsin
✍ Scribed by Marie-Thérèse Babonneau; Robert Jacquier; René Lazaro; Philippe Viallefont
- Publisher
- Elsevier Science
- Year
- 1989
- Tongue
- French
- Weight
- 286 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Peptide synthesis catalyzed by polyethyl
✍
Hubert F. Gaertner; Antoine J. Puigserver
📂
Article
📅
1988
🏛
John Wiley and Sons
🌐
English
⚖ 795 KB
Enzymatic reactions in aqueous-organic m
✍
H. Noritomi; H. Kise
📂
Article
📅
1987
🏛
Springer Netherlands
🌐
English
⚖ 165 KB
L-Dopa ester synthesis catalyzed by α-ch
✍
Evgeny N. Vulfson; Ghulam Ahmed; Iqbal Gill; Peter W. Goodenough; Igor A. Kozlov
📂
Article
📅
1990
🏛
Springer Netherlands
🌐
English
⚖ 282 KB
Peptide synthesis in aqueous–organic sol
✍
Kurt Nilsson; Klaus Mosbach
📂
Article
📅
1984
🏛
John Wiley and Sons
🌐
English
⚖ 896 KB
Enzymatic reactions in aqueous-organic m
✍
H. Kise; A. Hayakawa; H. Noritomi
📂
Article
📅
1987
🏛
Springer Netherlands
🌐
English
⚖ 231 KB
Large acceleration of α-chymotrypsin-cat
Large acceleration of α-chymotrypsin-catalyzed dipeptide formation by 18-crown-6 in organic solvents
✍
Dirk-Jan van Unen; Johan F. J. Engbersen; David N. Reinhoudt
📂
Article
📅
1998
🏛
John Wiley and Sons
🌐
English
⚖ 69 KB
The effects of 18-crown-6 on the synthesis of peptides catalyzed by ␣-chymotrypsin are reported. Lyophilization of the enzyme in the presence of 50 equivalents of 18-crown-6 results in a 425-fold enhanced activity when the reaction between the 2-chloroethylester of N-acetyl-L-phenylalanine and L-phe