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Enzymatic Resolution of 2,2,2-Trifluoro-1-(1-pyrenyl)ethanol with Lipases

✍ Scribed by Kato, Katsuya; Katayama, Masato; Fujii, Shozo; Kimoto, Hiroshi

Book ID
126634014
Publisher
Japan Science and Technology Information Aggregator, Electronic
Year
1997
Tongue
English
Weight
613 KB
Volume
61
Category
Article
ISSN
0916-8451

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The crystal structure of the title compound, C 15 H 14 N 2 OÁ-CF 3 CH 2 OH, which is the 2,2,2-trifluoroethanol (TFE) solvate of 5H-dibenzo[b,f]azepine-5-carboxamide (carbamazepine, CBZ), is reported. The asymmetric unit consists of two independent molecules of each component, CBZ and TFE.