## Abstract Spiegelmers are high‐affinity l‐enantiomeric oligonucleotide ligands (aptamers) that display high resistance to enzymatic degradation compared to d‐oligonucleotides. Spiegelmers belong to the third generation of aptamers, and are currently extensively investigated as potential therapeut
Enzymatic labelling of carcinoembryonic antigen with iodine-125
✍ Scribed by Andrzej Siuda; Barbara Lucka; Krystyna Russin
- Publisher
- John Wiley and Sons
- Year
- 1981
- Tongue
- French
- Weight
- 385 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0022-2135
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
Carcinoembryonic antigen /CEA/ was labelled with iodine‐125 using lactoperoxidase. The radiochemical yield of /^125^I/CEA was about 25% at the specific activity of about 30μCi/μg /1.1MBq/μg/. The percentage binding of /^125^I/CEA with specific anti‐CEA serum was determined in lyophilized samples during storage. The obtained /^125^I/CEA preparations can be utilized in radioimmunoassay kits for at least two months.
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