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Preparation of Bolton and Hunter's reagent for labelling proteins with iodine-125

✍ Scribed by B. Lucka; A. Siuda

Publisher
John Wiley and Sons
Year
1978
Tongue
French
Weight
115 KB
Volume
15
Category
Article
ISSN
0022-2135

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Preparation of the iodine-124 derivative
Preparation of the iodine-124 derivative of the Bolton–Hunter reagent ([124I]I-SHPP) and its use for labelling a VEGF antibody as a PET tracer
✍ Matthias Glaser; Veronica A. Carroll; David R. Collingridge; Eric O. Aboagye; Pa πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 French βš– 128 KB

## Abstract This study describes the radioiodination of an antibody specific to the vascular endothelial growth factor (VEGF), VG76e, with [^124^I]iodine to obtain a novel PET tracer for measurement of angiogenesis. __In vitro__ binding assays showed a significantly higher immunoreactive fraction w