Surfactant-coated lipases have been utilized as a biocatalyst for the resolution of racemic ibuprofen. S-(+)-ibuprofen was selectively transferred to the ester form by Mucor javanicus or Candida rugosa lipase. The enzymatic activity of lipases in organic media was remarkably enhanced by coating with
Enzymatic interesterification of triglyceride with surfactant-coated lipase in organic media
โ Scribed by Masahiro Goto; Muneharu Goto; Noriho Kamiya; Fumiyuki Nakashio
- Publisher
- John Wiley and Sons
- Year
- 1995
- Tongue
- English
- Weight
- 544 KB
- Volume
- 45
- Category
- Article
- ISSN
- 0006-3592
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The enantioselective recognition mechanism of secondary alcohol by lipases originated from Candida rugosa and Pseudomonas cepacia was elucidated on the basis of the kinetic study of the esterification of alcohol with lauric acid in isooctane. To obtain inherent kinetic parameters, we utilized a surf
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