Enzymatic dynamic kinetic resolution of epihalohydrins
β Scribed by Jeffrey H Lutje Spelberg; Lixia Tang; Richard M Kellogg; Dick B Janssen
- Book ID
- 108283741
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 309 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0957-4166
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π SIMILAR VOLUMES
The equilibration of a mixture of enantiomers or diastereoisomers prior Io or during kinetic resolution permits the isolation of a single isomer of one product in >50% yield. Examples of such processes involving bolh enantioselective and diastereoselective reactions are discussed. In some cases high
The use of transition-metal-enzyme combinations to effect tandem in situ racemisation and resolutions has extended the scope of dynamic kinetic resolutions. This methodology has signalled a more proactive stance to the racemisation process, which has traditionally relied on more fortuitous approache
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