Environmental influences on DNA superhelicity
โ Scribed by Brady, George W.; Satkowski, Michael; Foos, David; Benham, Craig J.
- Book ID
- 121476442
- Publisher
- Elsevier Science
- Year
- 1987
- Tongue
- English
- Weight
- 832 KB
- Volume
- 195
- Category
- Article
- ISSN
- 0022-2836
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Restriction fragments containing either leut (a rho-independent transcription termination site) and/or leut' (a rho-dependent transcription termination site) were cloned into plasmid pOL4. Treatment of plasmid-containing Escherichia coli strains with coumermycin resulted in loss of in vivo plasmid s
## Synopsis A quantity, called the linking number, is defined, which specifies the total number of t,wists in a circular helix. The linking number is invariant under continuous deformations of the ring and therefore enables one to calculate the influence of superhelical structures on the secondary