The reactions of4+aloacetophenones, further substituted bye -halo or phenyl groups, with triphewlphosphine lead to isolable enol tripheqlphosphonium halides. 2,3 Cyclic &-haloketones, as typified by H-bromocyclohexanone, give the ketophosphonium ha1ide.h We have foundthat
Enolization of the phosphoryl group
β Scribed by Tatjana A. Mastryukova; Martin I. Kabachnik
- Publisher
- John Wiley and Sons
- Year
- 1991
- Tongue
- English
- Weight
- 999 KB
- Volume
- 2
- Category
- Article
- ISSN
- 1042-7163
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β¦ Synopsis
Enolization of the phosphoryl group RR'P(O)CH(Y);Phfi--has been studied where Y =
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Trityloxyethylamino group was used for the protection of 5'-phosphoryl group of deoxyribonucleoside. This group is not only protecting group of phosphate also the intermediate for the synthesis of d-ppA and d-pppA. The synthesis of deoxyoligonucleotide with a defined sequence is accomplished very
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