Formation and alkylation of enolates from enol phosphorylated species
✍ Scribed by Irving J. Borowitz; E.W.R. Casper; R.K. Crouch
- Publisher
- Elsevier Science
- Year
- 1971
- Tongue
- French
- Weight
- 237 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
✦ Synopsis
The reactions of4+aloacetophenones, further substituted bye -halo or phenyl groups, with triphewlphosphine lead to isolable enol tripheqlphosphonium halides. 2,3 Cyclic &-haloketones, as typified by H-bromocyclohexanone, give the ketophosphonium ha1ide.h We have foundthat
📜 SIMILAR VOLUMES
The first tertiary alkylations, alkoxyalkylations, and aldehyde enolate allylations are described proceeding with low catalyst loading (0.1 mol % to 5 mol %). The reactions proceed in short times, can be performed without solvent and under ambient conditions.
Terminal alkenes of the type H 2 C C(OR 1 )X, in which R 1 is a tertiary alkyl or a 1-cyclopropylethyl group and X=Ph, OSiMe 2 Bu t , OEt or H, undergo radical-chain reactions with organic halides R 2 Hal to give carbonyl compounds R 2 CH 2 C( O)X.