## Abstract ## Background. Multidrug resistance (MDR) hampers chemotherapy in head and neck squamous cell carcinoma (HNSCC). There is little information about MDR mediating drug transporters in HNSCC. ## Methods. Nine HNSCC cell lines were characterized concerning drug transporter expression and
Enhancement of cytotoxicity of natural product drugs against multidrug resistant variant cell lines of human head and neck squamous cell carcinoma and breast carcinoma by tesmilifene
β Scribed by Peter J. Ferguson; Alayne R. Brisson; James Koropatnick; Mark D. Vincent
- Book ID
- 116334991
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 465 KB
- Volume
- 274
- Category
- Article
- ISSN
- 0304-3835
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An in vitro model of antibody-dependent cellular qtotoxicity (ADCC) was established, using squamous-cell carcinoma of the head and neck (SCCHN) targets, humanlmouse chimeric monoclonal adbodies (cMAbs) SF-25 and 323/A3 and human peripheral blood mononuclear cells (PBMC). We previously showed that na