An in vitro model of antibody-dependent cellular qtotoxicity (ADCC) was established, using squamous-cell carcinoma of the head and neck (SCCHN) targets, humanlmouse chimeric monoclonal adbodies (cMAbs) SF-25 and 323/A3 and human peripheral blood mononuclear cells (PBMC). We previously showed that na
β¦ LIBER β¦
The Role of Apoptosis in Antibody-Dependent Cell-Mediated Cytotoxicity against Monolayers of Human Squamous Cell Carcinoma of the Head and Neck Targets
β Scribed by Myung-Whun Sung; Shigeki Nagashima; Jonas T. Johnson; G.A.M.S. Van Dongen; Theresa L. Whiteside
- Book ID
- 112239567
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 903 KB
- Volume
- 171
- Category
- Article
- ISSN
- 0008-8749
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## Abstract Head and neck cancer is a challenging disease that is expected to account for greater than 500,000 new cases worldwide in 2008. Toxicity has impeded advances in chemotherapy and radiation for head and neck cancer, and the prognosis for patients with recurrent and/or metastatic disease r