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Enhancement of cytotoxic drug action on growth of human breast cancer cells by medroxyprogesterone acetate

✍ Scribed by Reed, M.J.; Ghilchik, M.W.; Braunsberg, H.; Shaikh, N.A.


Book ID
123180332
Publisher
Elsevier Science
Year
1990
Weight
136 KB
Volume
26
Category
Article
ISSN
0277-5379

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Exposure of cultured human breast cancer cells (MCF-7) to medroxyprogesterone acetate (MPA) prior to treatment with adriamycin (ADR) enhanced the effect of the cytotoxic drug on cell yield after further growth of viable cells. Pretreatment with oestradiol (E2) produced similar synergism, but no such

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