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Enhanced sialylation of recombinant human erythropoietin in Chinese hamster ovary cells by combinatorial engineering of selected genes

✍ Scribed by Son, Y.-D.; Jeong, Y. T.; Park, S.-Y.; Kim, J. H.


Book ID
125531960
Publisher
Oxford University Press
Year
2011
Tongue
English
Weight
293 KB
Volume
21
Category
Article
ISSN
0959-6658

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✍ Xuejun Gu; Bryan J. Harmon; Daniel I.C. Wang πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 183 KB πŸ‘ 1 views

Since sialic acid content is known to be a critical determinant of the biological properties of glycoproteins, it is essential to characterize and monitor sialylation patterns of recombinant glycoproteins intended for therapeutic use. This study reports site-and branchspecific differences in sialyla