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Enhanced sialylation of recombinant erythropoietin in genetically engineered Chinese-hamster ovary cells

✍ Scribed by Yeon Tae Jeong; One Choi; Young Dok Son; Seung Yeol Park; Jung Hoe Kim

Book ID
111718270
Publisher
Portland Press
Year
2009
Tongue
English
Weight
361 KB
Volume
52
Category
Article
ISSN
0885-4513

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## Abstract Glycosylation engineering strategies that are currently used to improve quality of recombinant glycoproteins involve the manipulation of glycosyltransferase and/or glycosidase expression. We explored the possibility that over expressing nucleotide sugar transporters, particularly the CM