Enhanced Mn-SOD Immunoreactivity in the Dopaminergic Neurons of Long-Evans Cinnamon Rats
โ Scribed by Dong Woon Kim; Tae-Beom Ahn; Jong Min Kim; Gye Sun Jeon; Je Hoon Seo; Beom S. Jeon; Sa Sun Cho
- Publisher
- Springer
- Year
- 2005
- Tongue
- English
- Weight
- 337 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0364-3190
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๐ SIMILAR VOLUMES
Long Evans Cinnamon (LEC) rats are an inbred strain with a mutation affecting a copper transporter. As a result, hepatic copper levels rise and the rats spontaneously develop hepatitis that is fatal in about 40% of the rats. The rats that die have been reported to develop anti-microsomal antibodies,
The Long-Evans Cinnamon rat is a mutant strain that contracts hereditary hepatitis and, eventually, spontaneous hepatocellular carcinoma. Because we found a corresponding gross copper accumulation in the liver of the rats, we examined whether the development of hepatitis in our rat system could be p
## Abstract Nicotinic acetylcholine receptors (nAChR) are widely distributed in the central nervous system, where they exert a modulatory influence on synaptic transmission. For the striatum, pharmacological evidence supports the presence of presynaptic ฮฑ3ฮฒ2\* and ฮฑ4ฮฒ2\* nAChR that modulate dopamin