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Enhanced expression of growth factors and imbalance between hepatocyte proliferation and apoptosis in the livers of rats fed a choline-deficient, l-amino acid-defined diet

โœ Scribed by Masaaki Onaga; Akio Ido; Satoru Hasuike; Hirofumi Uto; Akihiro Moriuchi; Jyunya Kato; Takeshi Hori; Katsuhiro Hayashi; Hirohito Tsubouchi


Book ID
108138176
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
606 KB
Volume
28
Category
Article
ISSN
1386-6346

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Alterations of the M6p/Igf2 receptor gen
โœ Toshifumi Tsujiuchi; Yasutaka Sasaki; Yasuo Oka; Hiroki Kuniyasu; Yoichi Konishi ๐Ÿ“‚ Article ๐Ÿ“… 2004 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 197 KB

## Abstract To elucidate whether the M6p/Igf2 receptor (M6p/Igf2r) gene might be involved in exogenous and endogenous liver carcinogenesis, we investigated its alteration in hepatocellular carcinomas (HCCs) induced by __N__โ€nitrosodiethylamine (DEN) and by a cholineโ€deficient Lโ€amino acidโ€defined (