𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Disturbance of DNA methylation patterns in the early phase of hepatocarcinogenesis induced by a choline-deficient L-amino acid-defined diet in rats

✍ Scribed by Kyoko Shimizu; Mariko Onishi; Eriko Sugata; Yui Sokuza; Chiharu Mori; Tomoki Nishikawa; Kanya Honoki; Toshifumi Tsujiuchi


Book ID
108583971
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
228 KB
Volume
98
Category
Article
ISSN
1347-9032

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Fhit gene alterations in hepatocarcinoge
✍ Toshifumi Tsujiuchi; Yasutaka Sasaki; Yasuo Oka; Yoichi Konishi; Masahiro Tsutsu 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 125 KB

## Abstract Alterations of the fragile histidine triad (__Fhit__) gene were investigated in rat hepatocarcinogenesis induced by a choline‐deficient L‐amino acid–defined (CDAA) diet. Males of the F344 strain, 6 wk of age, were fed a CDAA diet, and subgroups were killed at 2, 4, 12, 20, and 75 wk aft

CpG site hypermethylation of E-cadherin
✍ Toshifumi Tsujiuchi; Kyoko Shimizu; Yumi Itsuzaki; Mariko Onishi; Eriko Sugata; 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 188 KB

## Abstract We investigated DNA methylation patterns of E‐cadherin and Connexin26 (Cx26) genes in rat hepatocellular carcinomas (HCCs) induced by a choline‐deficient L‐Amino Acid‐defined (CDAA) diet. Six‐wks‐old F344 male rats were continuously fed with a CDAA diet for 75 wks, and were then killed.

Alterations of the M6p/Igf2 receptor gen
✍ Toshifumi Tsujiuchi; Yasutaka Sasaki; Yasuo Oka; Hiroki Kuniyasu; Yoichi Konishi 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 197 KB

## Abstract To elucidate whether the M6p/Igf2 receptor (M6p/Igf2r) gene might be involved in exogenous and endogenous liver carcinogenesis, we investigated its alteration in hepatocellular carcinomas (HCCs) induced by __N__‐nitrosodiethylamine (DEN) and by a choline‐deficient L‐amino acid‐defined (