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Different Roles of 8-Hydroxyguanine Formation and 2-Thiobarbituric Acid-reacting Substance Generation in the Early Phase of Liver Carcinogenesis Induced by a Choline-deficient,l-Amino Acid-defined Diet in Rats

✍ Scribed by Nakae, Dai ;Mizumoto, Yasushi ;Yoshiji, Hitoshi ;Andoh, Nobuaki ;Horiguchi, Kohsuke ;Shiraiwa, Kazumi ;Kobayashi, Eisaku ;Endoh, Takehiro ;Shimoji, Naoshi ;Tamura, Kazutoshi ;Tsujiuchi, Toshifumi ;Denda, Ayumi ;Konishi, Yoichi


Book ID
108580833
Publisher
Wiley (Blackwell Publishing)
Year
1994
Tongue
English
Weight
613 KB
Volume
85
Category
Article
ISSN
0910-5050

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## Abstract To elucidate whether the M6p/Igf2 receptor (M6p/Igf2r) gene might be involved in exogenous and endogenous liver carcinogenesis, we investigated its alteration in hepatocellular carcinomas (HCCs) induced by __N__‐nitrosodiethylamine (DEN) and by a choline‐deficient L‐amino acid‐defined (