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Enhanced Antiproliferative and Cytotoxic Effects of Mitochondria-targeted Tocopherol in Breast Cancer Cells

✍ Scribed by Joy Joseph; Jin-Hwan Kim; Gang Cheng; Jacek Zielonka; Balaraman Kalyanaraman

Book ID
113631360
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
397 KB
Volume
49
Category
Article
ISSN
0891-5849

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## Abstract Chemotherapy employing paclitaxel and docetaxel is widely used for treating early‐stage breast cancer and metastasis, which is frequently associated with overexpression of epidermal growth factor receptor (EGFR) and resistance to apoptosis. ZD6474, a dual tyrosine kinase inhibitor of EG