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Selective killing of breast cancer cells by mitochondria-targeted α-tocopherol

✍ Scribed by Jacek Zielonka; Gang Cheng; Jin-Hwan Kim; Joy Joseph; Balaraman Kalyanaraman

Book ID
113632425
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
82 KB
Volume
51
Category
Article
ISSN
0891-5849

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## Abstract We hypothesized that over‐expression of estrogen receptor (ER) in hormone‐sensitive breast cancer could be harnessed synergistically with the tumor‐migrating effect of porphyrins to selectively deliver estrogen‐porphyrin conjugates into breast tumor cells, and preferentially kill the tu