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Enhanced and prolonged efficacy of superantigen-induced cytotoxic T lymphocyte activity by interleukin-2 in vivo

✍ Scribed by Hans Belfrage; Mikael Dohlsten; Gunnar Hedlund; Terje Kalland


Publisher
Springer-Verlag
Year
1995
Tongue
English
Weight
737 KB
Volume
41
Category
Article
ISSN
0340-7004

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## Abstract Cholera toxin irreversibly activates a 43‐kDa guanosine triphosphate (GTP)‐binding protein by adenosine diphosphate ribosylation, resulting in activation of adenylate cyclase and increased intracellular levels of cyclic adenosine monophosphate (cAMP). Because increases in intracellular