## Abstract The effects of interleukin 2 (IL2) on the __in vitro__ and __in vivo__ activity of cytotoxic T cells have been studied. IL2 was produced by W/Fu rat spleen cells cultured with concanavalin A. The IL2 thus prepared gave an optimal Tβcell growthβpromoting effect at a concentration of 5β20
In vivo evaluation of the effects of interleukins 2, 4 and 7 on enhancing the immunotherapeutic efficacy of anti-tumor cytotoxic T lymphocytes
β Scribed by David H. Lynch; Anthony E. Namen; Robert E. Miller
- Publisher
- John Wiley and Sons
- Year
- 1991
- Tongue
- English
- Weight
- 892 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0014-2980
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Cholera toxin irreversibly activates a 43βkDa guanosine triphosphate (GTP)βbinding protein by adenosine diphosphate ribosylation, resulting in activation of adenylate cyclase and increased intracellular levels of cyclic adenosine monophosphate (cAMP). Because increases in intracellular
The in vivo anti-tumor activity of 2 recombinant cytokines, interleukin-2 (rlL-2) and human hybrid interferon alpha (rHulFN-aA/D), were tested using the murine reticulum cell sarcoma M5076. Experimental hepatic metastases, following i.v. injection of tumor cells, and tumor growth and spontaneous met