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Immunodominance of cytotoxic T lymphocyte epitopes co-injected in vivo and modulation by interleukin-12

✍ Scribed by Gérard Eberl; Benedikt Kessler; Lucie Peduto Eberl; Michael J. Brunda; Danila Valmori; Giampietro Corradin


Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
734 KB
Volume
26
Category
Article
ISSN
0014-2980

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## Abstract Cholera toxin irreversibly activates a 43‐kDa guanosine triphosphate (GTP)‐binding protein by adenosine diphosphate ribosylation, resulting in activation of adenylate cyclase and increased intracellular levels of cyclic adenosine monophosphate (cAMP). Because increases in intracellular