𝔖 Bobbio Scriptorium
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Engineering the Assembly Pathway of the Baculovirus-Insect Cell Expression Systema

✍ Scribed by TSU-AN HSU; JOSEPH J. EIDEN; MICHAEL J. BETENBAUGH

Book ID
119871110
Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
723 KB
Volume
721
Category
Article
ISSN
0890-6564

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The inability to produce eukaryotic glycoproteins with complex N-linked glycans is a major limitation of the baculovirus-insect cell expression system. Recent studies have demonstrated that metabolic engineering can be used to extend the glycoprotein processing capabilities of lepidopteran insect ce