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Biochemical Analysis of the N-Glycosylation Pathway in Baculovirus-Infected Lepidopteran Insect Cells

✍ Scribed by Donald L. Jarvis; Eric E. Finn


Book ID
112270683
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
909 KB
Volume
212
Category
Article
ISSN
0042-6822

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Engineering N-glycosylation pathways in
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The inability to produce eukaryotic glycoproteins with complex N-linked glycans is a major limitation of the baculovirus-insect cell expression system. Recent studies have demonstrated that metabolic engineering can be used to extend the glycoprotein processing capabilities of lepidopteran insect ce