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Modifying the insect cell N-glycosylation pathway with immediate early baculovirus expression vectors

✍ Scribed by Jarvis, Donald L.; Finn, Eric E.

Book ID
109908596
Publisher
Nature Publishing Group
Year
1996
Tongue
English
Weight
635 KB
Volume
14
Category
Article
ISSN
1087-0156

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✍ Donald L Jarvis; Ziad S Kawar; Jason R Hollister πŸ“‚ Article πŸ“… 1998 πŸ› Elsevier Science 🌐 English βš– 548 KB

The inability to produce eukaryotic glycoproteins with complex N-linked glycans is a major limitation of the baculovirus-insect cell expression system. Recent studies have demonstrated that metabolic engineering can be used to extend the glycoprotein processing capabilities of lepidopteran insect ce