✦ LIBER ✦

Engineered Biosynthesis of Novel Polyketides: Properties of the whiE Aromatase/Cyclase

✍ Scribed by Alvarez, Miguel A.; Fu, Hong; Khosla, Chaitan; Hopwood, David A.; Bailey, James E.

Book ID: 109902433
Publisher: Nature Publishing Group
Year: 1996
Tongue: English
Weight: 606 KB
Volume: 14
Category: Article
ISSN: 1087-0156
DOI: 10.1038/nbt0396-335

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Engineered Biosynthesis of Novel Polyket

Engineered Biosynthesis of Novel Polyketides from Streptomyces Spore Pigment Polyketide Synthases

✍ Yu, Tin-Wein; Shen, Yuemao; McDaniel, Robert; Floss, Heinz G.; Khosla, Chaitan; 📂 Article 📅 1998 🏛 American Chemical Society 🌐 English ⚖ 196 KB

Engineered Biosynthesis of Novel Polyket

Engineered Biosynthesis of Novel Polyketides: Dissection of the Catalytic Specificity of the act Ketoreductase

✍ Fu, Hong; Ebert-Khosla, Susanne; Hopwood, David A.; Khosla, Chaitan 📂 Article 📅 1994 🏛 American Chemical Society 🌐 English ⚖ 1003 KB

Engineered Biosynthesis of Novel Polyket

Engineered Biosynthesis of Novel Polyketides: Regiospecific Methylation of an Unnatural Substrate by the tcmO O -Methyltransferase †

✍ Fu, Hong; Alvarez, Miguel A.; Khosla, Chaitan; Bailey, James E. 📂 Article 📅 1996 🏛 American Chemical Society 🌐 English ⚖ 272 KB

Biosynthesis of Complex Polyketides in a

Biosynthesis of Complex Polyketides in a Metabolically Engineered Strain of E. coli

✍ Pfeifer, B. A. 📂 Article 📅 2001 🏛 American Association for the Advancement of Scienc 🌐 English ⚖ 256 KB

Rational Design and Engineered Biosynthe

Rational Design and Engineered Biosynthesis of a Novel 18-Carbon Aromatic Polyketide

✍ Kramer, Peter J.; Zawada, Robert J. X.; McDaniel, Robert; Hutchinson, C. Richard 📂 Article 📅 1997 🏛 American Chemical Society 🌐 English ⚖ 250 KB

Engineered biosynthesis of novel polyket

Engineered biosynthesis of novel polyketides: evidence for temporal, but not regiospecific, control of cyclization of an aromatic polyketide precursor

✍ Hong Fu; David A. Hopwood; Chaitan Khosla 📂 Article 📅 1994 🏛 Elsevier Science 🌐 English ⚖ 662 KB

## Background: Aromatic polyketide synthases (PKSs) catalyze the formation and cyclization of polyketide chains of variable lengths, generating a family of compounds of proven medical significance. Initial control over the regiospecificity of cyclization is believed to be exercised by the minimal