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Enforced expression of human bcl-2 in CD4+ T cells enhances human herpesvirus 7 replication and induction of cytopathic effects

✍ Scribed by Paola Secchiero; Lucia Bertolaso; Davide Gibellini; Daniele Ricci; Kristi Bemis; Silvano Capitani; Robert C. Gallo; Giorgio Zauli


Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
232 KB
Volume
28
Category
Article
ISSN
0014-2980

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To generate non-small cell lung cancer (NSCLC)-reactive lymphocytes, we transfected an HLA-A2-expressing human NSCLC line (1355) with the cDNA encoding the lymphocyte co-stimulatory molecule CD80. Following selection in G418, 1355.7 demonstrated stable cell-surface expression of CD80. Allogeneic mix