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Analysis of allelic expression patterns of IL-2, IL-3, IL-4, and IL-13 in human CD4+ T cell clones

✍ Scribed by Jean-Pierre Bayley; Aleida M. Bakker; Eric L. Kaijzel; Eddy A. Wierenga; Tineke C. T. M. van der Pouw-Kraan; Tom W. J. Huizinga; Cornelis L. Verweij


Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
199 KB
Volume
33
Category
Article
ISSN
0014-2980

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## Abstract CD4^+^ T lymphocytes are required to induce spontaneous autoimmune diabetes in the NOD mouse. Since pancreatic β cells upregulate Fas expression upon exposure to pro‐inflammatory cytokines, we studied whether the diabetogenic action of CD4^+^ T lymphocytes depends on Fas expression on t